A favorite venture investing cliché is that a company is only as good as its people. To have a chance at success, an entrepreneur must be able to attract and retain bright, motivated, and high-integrity colleagues. To have a chance at transformative success, these bright, motivated, high-integrity colleagues must be brought together as a team, and supported and developed so that their strengths can be honed and gaps filled or avoided. Building a cohesive and high-functioning team is often a stumbling block for scientist-entrepreneurs more comfortable crunching numbers than given pep talks. Hire the best people you can find, be authentic, and never stray from your values, and you’ll be off to a good start.